The yeast Candida albicans and related species are responsible for various types of candidiasis, for example, topical or vaginal candidiasis. (As used herein, the term “antiperspirant” includes compositions intended to prevent perspiration, as well as those intended to prevent odor due to perspiration.) Substituted 1,8-dihydroxyanthraquinones have also been found in various species of aloe such as Aloe barbadensis, Aloe ferox (which also belong to the Asphodelaceae family) and species of rhubarb such as Rheum rhabarbarum and Rheum palmatum (Chinese rhubarb). In pigs, Bulbine natalensis leaf gel extracts healed wounds faster and better than untreated wounds. In development at this stage is a range of SKIN CARE products as well as a new range of soaps, and a scalp lotion. How does it work? Like Aloe vera, Bulbine frutescens contains glycoproteins which have give it similar healing properties. By reducing or eliminating these microorganisms, the unpleasant odor can be reduced or completely eliminated. Bulbine Bulbine frutescens . The main active ingredient in XYZ Smart Collagen is known as Bulbine frutescens leaf sap. It is this potent sap which is used in our products, a pure blessing from God's healing hands. There are very few rules in gardening, but perhaps the most important one is to work within your zone. The use in the therapeutic field comprises, for example, application of the Bulbine frutescens extract for treatment or prevention of diseases and injuries of the skin and mucous membranes. All rights reserved. Bulbinella (Bulbine frutescens) is an indigenous South African stalwart which we are enormously proud of. Bulbine extract (Bulbine Frutescens Leaf Juice), from Swiss research, stimulates the creation of new cells, the skin becomes firmer and wrinkles will be filled in. The anthraquinones in the aloe and rhubarb species lack the 2 acetylphloroglucine methyl ether group which is present in knipholone. At the heart of Afari skincare, is Bulbine frutescens, a small indigenous shrub that grows in the dry valleys of southern Africa.This succulent plant contains a gel-like sap in its leaves, which has been used by generations of traditional healers as a remedy for skin injuries due to the soothing, anti-inflammatory effect of the sap. ), Birkäuser Basel). The Bulbine frutescens extract consists of many different chemical units, including polysaccharides. Complete kill after 2 hours. As mentioned previously, cosmetic or pharmaceutical compositions comprising the Bulbine frutescens extract may also include one or more pharmaceutically or cosmetically acceptable vehicles or excipients. These joziknipholones have exhibited an effect in vitro against the chloroquine-resistant strain K1 of the malaria pathogen Plasmodium falciparum and a moderate effect against L5178Y leukemia lymphoma mouse cells. It has been found in a completely unexpected manner that the Bulbine frutescens extract has antimicrobial properties. For more information click here It has a jelly like sap which can be applied to the skin. Bulbine Frutescens is a South African aloe-like succulent plant that has powerful anti-itch properties. The Bulbine frutescens extract is used in the therapeutic or cosmetic fields and has an especially good effect on diseases of the skin and mucous membranes, in particular infections or inflammations such as fungal diseases, in prevention and/or curing injuries to the skin and mucous membranes, in particular burn wounds, as a … (2) Destroying the hydrogen peroxide by adding one or more pharmaceutically or cosmetically acceptable acids while stirring until the peroxide value of the solution is less than 0.02 meq O/kg; (3) Adjusting the pH to 3.0 to 4.0 by adding, as necessary, one or more pharmaceutically or cosmetically acceptable acids; and. From April to August the plant bears yellow, orange or white blossoms in dense elongated flower clusters with a length of up to 30 cm and with a bearded stamen. Die Erfindung betrifft ein Bulbine-frutescens-Gel, das durch Verarbeitung der Blätter der Bulbine fructescens, Behandlung mit Wasserstoffperoxid, Beseitigung des restlichen Wasserstoffperoxids und Stabilisierung unter Verwendung eines geeigneten Stabilisierungsmittels in stabiler Form bereitgestellt wird. All trademarks are the property of their respective owners. Bulbine frutescens is a unique plant with incredible healing, soothing and moisturising qualities. Nevertheless there is a high tolerability in use, whereby at the same time the properties of the skin and mucous membranes are influenced in a positive sense. Bulbine frutescens is native to South Africa. The effect is to some extent far superior to that of commercial products, and the natural microflora of the skin and mucous membranes is not damaged but instead remains intact. This soap is not perfumed and is of vegetable (not animal) ingredients. The sap from the leaves has wonderful skin healing properties. In some cases, hydrogen sulfide, methyl mercaptan and dimethyl sulfide make a significant contribution to mouth odor in addition to various alkylated amines. Bulbine natalensisand Bulbine frutescensof the Asphodelaceae family are indigenous to only southern Africa and are widely used as a skin remedy. Rather, any dosage form or formulation which includes the extract (or a product processed further from it) as an active ingredient is contemplated. The resulting extract can be formulated as is or it may be subjected to a suitable further processing and then incorporated into a suitable formulation form. On the other hand chlorhexidine and hydrogen peroxide have an extremely harmful effect on the commensal microflora in the oral cavity. Fungus infections of the nails and feet are caused by fungi. Test formulaons: Emulsion without Bulbine Frutescens Extract (placebo); Emulsion with 3 % Bulbine Frutescens … Bulbine has become a popular plant in frost-free regions because it is drought tolerant, grows well in poor soils, and blooms repeatedly with cheerful yellow and orange flowers. In addition to a wide variety of therapeutic uses, it has been found that the Bulbine frutescens extract may also be used for body care as well as other cosmetic uses. Bulbine has a wide range of medicinal uses such as burns, itchy skin and wounds. The ingredient also promotes skin recovery processes and increases skin hydration via natural lipid synthesis. Preferred administration pathways include transdermally and topically. Arabinogalactan proteins (AGPs) function as signal molecules between the cells and as an adhesive for closing wounds on plants. The extract may be used in the cosmetic and therapeutic fields. Choosing plants that grow and thrive in your particular climate is the very first step toward having a beautiful garden . The following description of certain examples of the invention should not be used to limit the scope of the present invention. It grows easily and robustly, flowers well for long periods and branches much to cover unsightly bare patches of even poor soil. While a variety of compositions and methods have been made and used, it is believed that no one prior to the inventor has made or used an invention as described herein. These SkinMedica® products are not intended to be drug products that diagnose, treat, cure, or prevent any disease or condition. It should also be noted that the phrase “Bulbine frutescens extract” or “extract” as used in herein is not necessarily limited to particular forms of administration or formulations. This website uses cookies and other technologies to personalize content and to show you more personalized ads (for example, Google Ads and Facebook) on this and other websites, as well as provide you with social media features on this website (such as, Facebook, Twitter, LinkedIn). The microbiological condition and the presence of pathogenic microorganisms in the extract end product may be controlled according to the methods described in the various pharmacopoeias such as the European Pharmacopoeia and/or the United States Pharmacopoeia such that the aerobic microbe count is less than 100 CFU/g, or even 10 CFU/g or less. For example, the extract provides a highly active agent in antiperspirant and/or deodorant compositions. It forms a clump about 1 ft. high and 2-3 ft. wide and is cold hardy to Zone 8. Mild redness, peeling, and irritation are expected when using these products. However any other stirrers may also be used. BULBINE FRUTESCENS EXTRACT IN VITRO STUDY Test design: Double-blind, placebo-controlled, randomised, half-sided; Test subjects: 21 female subjects, Caucasian skin, 45 – 65 years (average 59). Keep out of reach of children. Placebo-controlled experiments were conducted, showing that rinsing out the mouth twice a day with 10% aqueous solution of the Bulbine frutescens extract completely eliminates unwanted mouth odor. Ethlop. This plant is ideal to grow and is a useful … If you are new to SkinMedica® or just want to learn more about ouraward-winning products, this is the perfect place to start. The dosage of the Bulbine frutescens extract depends on, among other things, the dosage form, the intended purpose, the impairment to be treated, the disease or disorder, the user, the specifically selected vehicles and/or excipients. These microorganisms are usually difficult to eliminate because they settle not only on the surface of the skin or nails but are also present in the subcutaneous tissue. (2000) and Ghuman and Coopoosamy (2011) Bulbine natalensis Baker, Xanthorrhoeaceae: Ibhucu: Leaves, roots and leave sap: Applied directly to skin Many South Africans plant Bulbine frutescens. In pigs, Bulbine natalensis leaf gel extracts healed wounds faster and better than untreated wounds. The disadvantage of methods under an elevated temperature lies in the risk of conversion of the anthraquinones glycosides to the corresponding aglycones which are sparingly soluble/insoluble in water and thus reduce the effect of the Bulbine frutescens extract. We have also developed the TIMOLA® Skin Care range that showcases the many exceptional characteristics and daily uses of Bulbine … For example, the elasticity of the skin and the strength of the skin increases, while there is a long-lasting positive influence on the water balance of the skin as well as cell differentiation and cell proliferation. 2012 Dec 18;144(3):523-32. doi: 10.1016/j.jep.2012.09.034. The extract may be obtained by treating the juice obtained from Bulbine frutescens leaves with peroxide (particularly, hydrogen peroxide), and thereafter at least partially destroying the peroxide with one or more acids so as to produce a Bulbine frutescens extract. Bulbine is unusual and hard to find presently. Staphylococcus and Streptococcus species (aerobic gram-positive cocci): inoculation 104 CFU/g. This plays a role in particular in patients with a weakened immune system, for example, in diabetes or AIDS patients. For more information, including a list of the categories of third parties to whom we disclose your personal information, please refer to our California Privacy Policy or for additional options please check your browser’s settings. The efficacy of these agents is therefore very restricted. The Bulbine frutescens extract is thus superior to traditional pharmaceutical preparations, including preparations for oral disinfection based on chlorhexidine gluconate and hydrogen peroxide. Botanica Natural Products produces and supplies indigenous plant extracts, such as Bulbine frutescens, and oils in a socially and environmentally sustainable manner for the cosmeceutic and nutraceutic industries. Infections due to anthropophilic pathogens, for example, Trichophyton rubrum are usually less intense but are more chronic than infections with zoophilic pathogens such as Trichophyton mentagrophytes. Not use Retinol complex if you are pregnant, lactating, or it be. 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